1992년 ~ 1996년 Bachelor of Veterinary Medicine(DVM), College of Veterinary Medicine, Chungnam National University, Daejeon, Korea

1996년 ~ 1998년Master of Veterinary Medicine, College of Veterinary Medicine, Chungnam National University, Daejeon, Korea

1998년 ~ 2001년PhD of Veterinary Medicine, College of Veterinary Medicine, Chungnam National University, Daejeon, Korea

2001. 03 ~ 2005. 09Senior Research Scientist (Military service) Technical Research Center, BioLeaders Corporation, Daejeon, Korea

2005. 10 ~ 2006. 06Senior Research Scientist Technical Research Center, BioLeaders Corporation, Daejeon, Korea

2006. 08 ~ 2007. 12Research fellow Microbiology and Molecular Genetics, Tumor Virology Division, Harvard Medical School (Advisor : Dr. Jae U. Jung)

2008. 01 ~ 2010. 02Research fellow Molecular Microbiology and Immunology, Harlyne J. Norris Cancer Research Center, University of Southern California (Advisor : Dr. Jae U. Jung)

2010. 03 ~ 2014. 02Assistant Professor Veterinary Microbiology, College of Veterinary Medicine, Chungnam National University

2014. 03 ~ 2018. 02Associate Professor Veterinary Microbiology, College of Veterinary Medicine, Chungnam National University

2018. 03 ~ PresentProfessor Veterinary Microbiology, College of Veterinary Medicine, Chungnam National University, Daejeon, Korea

MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria. EMBO Journal. 2023. e113481. (*Co-corresponding Authors)

Foot-and-mouth disease virus non-structural protein 2B downregulates the RLR signaling pathway via degradation of RIG-I and MDA5. Frotiers in Immunology. 2022. 13: 1020262.

Regulation of antiviral innate immune signaling and viral evasion following viral genome sensing. Experimental & Molecular Medicine. 2021. 53(11):1647.

Negative regulation of the NEMO signaling by the ubiquitin E3 ligase MARCH2. EMBO Journal. 2020. 39(21):e105139.

Foot-and-Mouth disease virus VP1 target the MAVS to inhibit type-I interferon signaling and VP1 E83K mutation results in virus attenuation. PLOS Pathogens. 2020. 16(11):e1009057

SHP Controls the Virus-Mediated Antiviral Immune Response by Targeting CBP in the Nucleus. Cell Reports. 2019. 14: 2015-2118.

Fas-associated factor 1 Mediates NADPH Oxidase-Induced Reactive Oxygen Species Production and Proinflammatory Responses in Macrophages against Listeria Infection. PLOS Pathogens. 2019. 14;15(8):e1008004

Gadd45β promotes regeneration after injury through TGFβ-dependent restitution in experimental colitis. Experimental & Molecular Medicine. 2019. 51: 128. (*Co-corresponding Authors)

FAS-associated factor-1 positively regulates Type I interferon response to RNA virus infection by targeting NLRX1. PLOS Pathogens. 2017. 13(5): e1006398.

Infection-specific phosphorylation of glutamyl-prolyl tRNA synthetase induces antiviral immunity by promoting MAVS stabilization. Nature Immunology. 2016. 17: 1252-1262. (*Co-corresponding Authors)

HDAC6 regulates cellular viral RNA sensing by deacetylation of RIG-I. EMBO Journal. 2016. 35: 429-442. (*Co-corresponding Authors)(Highlighted in Nature Immunology. 2016)

The Mitochondrial Ubiquitin Ligase MARCH5 Resolves MAVS Aggregates during Antiviral Signaling. Nature Communications. 2015. 6:7910. (*Co-corresponding Authors)

Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation. Cell Host & Microbe. 2012. 11:264-276. (*Co-First Authors)

FLIP-mediated autophagy in cell death control. Nature Cell Biology. 2009 11:1355-62. (주저자)

Immunogenicity of surface displayed viral antigens on Salmonella carrier vaccine. Nature Biotechnology. 2000. 18:645-648. (주저자)